The Hyper-Kamiokande Experiment

The Hyper-Kamiokande experiment is a next generation underground water Cherenkov detector, based on the highly successful Super-Kamiokande experiment. It will serve as a far detector of a long baseline neutrino experiment for the J-PARC neutrino beam, with the main focus the determination of CP violation, and will also be a detector capable of observing - far beyond the sensitivity of the Super-Kamiokande detector - proton decay, atmospheric neutrinos, and neutrinos from astronomical sources

Expression of Interest: The Atmospheric Neutrino Neutron Interaction Experiment (ANNIE)

Neutron tagging in Gadolinium-doped water may play a significant role in reducing backgrounds from atmospheric neutrinos in next generation proton-decay searches using megaton-scale Water Cherenkov detectors. Similar techniques might also be useful in the detection of supernova neutrinos. Accurate determination of neutron tagging efficiencies will require a detailed understanding of the number of neutrons produced by neutrino interactions in water as a function of momentum transferred. We propose the Atmospheric Neutrino Neutron Interaction Experiment (ANNIE), designed to measure the neutron yield of atmospheric neutrino interactions in gadolinium-doped water. An innovative aspect of the ANNIE design is the use of precision timing to localize interaction vertices in the small fiducial volume of the detector. We propose to achieve this by using early production of LAPPDs (Large Area Picosecond Photodetectors). This experiment will be a first application of these devices demonstrating their feasibility for Water Cherenkov neutrino detectors.Comment: Submitted for the January 2014 Fermilab Physics Advisory Committee meetin

Inclusive Measure of |V_ub| with the Analytic Coupling Model

By analyzing B -> X_u l nu_l spectra with a model based on soft-gluon resummation and an analytic time-like QCD coupling, we obtain |V_ub| = (3.76 +-0.13 +- 0.22)*10^(-3), where the first and the second error refers to experimental and theoretical errors, respectively. The V_ub value is obtained from the available measured semileptonic branching fractions in limited regions of the phase-space. The distributions in the lepton energy E_l, the hadron invariant mass m_X, the light-cone momentum P_+ = E_X - p_X, together with the double distributions in (m_X,q^2) and (E_l,s_h^max), are used to select the phase-space regions. The q^2 is the dilepton squared momentum and s_h^max is the maximal m_X^2 at fixed q^2 and E_l. The V_ub value obtained is in complete agreement with the value coming from exclusive B decays and from an over-all fit to the Standard Model parameters. We show that the slight disagreement (up to +2 sigma) with respect to previous inclusive measurements is not related to different choices for the b (and c) masses but to a different modelling of the threshold (Sudakov) region.Comment: 19 pages, 2 figures, revised version accepted in Eur.Phys.J.

Evaluation of a large set of patients with Autoimmune Polyglandular Syndrome from a single reference centre in context of different classifications

Purpose: To characterize patients with APS and to propose a new approach for their follow-up. Query ID="Q1" Text="Please check the given names and familynames." Methods: Monocentric observational retrospective study enrolling patients referred to the Outpatients clinic of the Units of Endocrinology, Diabetology, Gastroenterology, Rheumatology and Clinical Immunology of our Hospital for Autoimmune diseases. Results: Among 9852 patients, 1174 (11.9%) [869 (73.9%) female] were diagnosed with APS. In 254 subjects, the diagnosis was made at first clinical evaluation (Group 1), all the other patients were diagnosed with a mean latency of 11.3 ± 10.6 years (Group 2). Group 1 and 2 were comparable for age at diagnosis (35.7 ± 16.3 vs. 40.4 ± 16.6 yrs, p =.698), but different in male/female ratio (81/173 vs 226/696, p =.019). In Group 2, 50% of patients developed the syndrome within 8 years of follow-up. A significant difference was found after subdividing the first clinical manifestation into the different outpatient clinic to which they referred (8.7 ± 8.0 vs. 13.4 ± 11.6 vs. 19.8 ± 8.7 vs. 7.4 ± 8.1 for endocrine, diabetic, rheumatologic, and gastroenterological diseases, respectively, p <.001). Conclusions: We described a large series of patients affected by APS according to splitters and lumpers. We propose a flowchart tailored for each specialist outpatient clinic taking care of the patients. Finally, we recommend regular reproductive system assessment due to the non-negligible risk of developing premature ovarian failure

Averages of b-hadron properties at the end of 2006

This article reports the world averages for measurements on b-hadron properties obtained by the Heavy Flavor Averaging Group (HFAG) using the available results at the end of 2006. In the averaging, the input parameters used in the various analyses are adjusted (rescaled) to common values, and all known correlations are taken into account. The averages include lifetimes, neutral meson mixing parameters, parameters of semileptonic decays, branching fractions of B decays to final states with open charm, charmonium and no charm, and measurements related to CP asymmetries.This article reports the world averages for measurements on b-hadron properties obtained by the Heavy Flavor Averaging Group (HFAG) using the available results at the end of 2006. In the averaging, the input parameters used in the various analyses are adjusted (rescaled) to common values, and all known correlations are taken into account. The averages include lifetimes, neutral meson mixing parameters, parameters of semileptonic decays, branching fractions of B decays to final states with open charm, charmonium and no charm, and measurements related to CP asymmetries